Butter or spray a 13x9 pan.
Spread cream cheese on six slices of bread. Spread preserves on top of cream cheese. Place in pan. Arrange blueberries evenly over the preserves. Top with remaining bread slices.
Beat eggs well then mix in milk or cream and flavorings. Pour evenly over the bread. Cover with plastic wrap and refrigerate overnight.
Preheat oven to 375. Tip pan and spoon any extra egg mixture over tops of the bread. Cover with foil. Bake 30-45 min. or until all liquid is absorbed. Allow it to sit a few minutes before removing from the pan.