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Purchasing the property of Dr. Brown Ismael at 217 S. Main St., Dr. E.P. Guerrant (1888-1964) was off to an auspicious beginning. The location of his practice in Winchester, KY in 1913 was not a careless decision. His own father, Edward O. Guerrant, M.D., D.D. (1836-1916) was a renowned Presbyterian evangelist and physician to the highland peoples of the Appalachian Mountains. During his tour of service with Gen. John Hunt Morgan in the Confederate Army, Dr. E.O. Guerrant was taken back by the sparse or non-existent spiritual and health needs of the mountain people of Kentucky and, following graduation from seminary and medical school, gave the next forty years of his life to their betterment. At his death in 1916, God had blessed his work by creating: three orphanages, two colleges, fifty-six churches, schools, and mission houses, that touched the lives of 40,000 pupils, eighty-four salaried workers, hundreds of unsalaried volunteers, 362 evangelists, and 6,304 salvations for the Kingdom. Twelve years would pass before a more spacious building located at 217 S. Main would be purchased in 1927. With $8,000 of his own money, Dr. E.P. Guerrant purchased the Edwardian architectural home and promptly placed it under the auspices of the Home Missions Department of the Southern Presbyterian Church. Two years later, on September 15, 1929, the Articles of Incorporation of the Edward O. Guerrant Memorial Association, named in honor of his evangelist/physician father, would be established. The articles present the goals of the mountain mission hospital: "to own and operate a mission hospital...to especially aid and serve the Southern people in our mountain districts; and no charge shall be made for those who are too poor to pay, nor shall any medical or surgical fee be charged to any mission worker or preacher or their dependents who are giving their lives to the Church's work."
Even through D.E.P. Guerrant opened his private practice in the McEldowney building in Court Street in 1913, he had not dismissed his fathers' exhortations to start a mountain mission clinic. In less than a year, he convinced the Ruby Chapter of the Daughters of the American Revolution to fund his effort to begin Winchester's first hospital.
Medical trips by Dr. E.P. Guerrant and his staff into the mountains of Eastern Kentucky continued for many years. Donations of every conceivable item poured into the mission hospital: clothing, bandages, medical equipment, sewing machines, furniture, farm equipment, produce and animals, and countless monetary donations, of which the largest (Mary Graddy Kendall and Hayden Kendall) donation helped to build the present Nurse's Home. But, no donation could match the sacrifice of Dr. E.P., his wife Lucy Mae, countless nurses such as Verda Brassfield, and the hundreds of volunteers who so generously gave without asking for anything in return than to remember Christ who made it all possible.
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